iNEXT course: “X-ray and neutron diffraction studies of macromolecules: from data collection to structures”

May 15-May 19, 2017

This is an intensive course, organized from May-15 to May-19, 2017 at the Faculty of Biochemistry and Molecular Medicine, University of Oulu in Oulu, Finland. It is organized in the context of the iNEXT Horizon2020 project (http://www.inext-eu.org ), together with Diamond (Oxford, UK), Biocenter Oulu and the Health and Biosciences Doctoral Programme of the University of Oulu. The course will include an introduction on the methods of protein crystallography (Rupp), neutron crystallography (Oksanen/Podjarny) and SAXS/SANS-approaches (Svergun). Also data collection at synchrotrons (Thunnissen), new perspectives when using the new long-wavelength beamline at Diamond (Wagner) and when using XFEL-technology (Hajdu) will be addressed. Tutorials include the validation tools of the PDB-deposition server (Rupp), as well as data processing (DIALS, Waterman; XDS, Rower), experimental phasing (SHELX, Gruene),  molecular replacement phasing (CCP4, Lebedev) and neutron structure refinement (Oksanen, Podjarny). Remote data collection (Diamond, Aller, Powell) of crystals from participating students is scheduled for the last day of the course. The course provides extensive opportunities for the students to work with the presented software in our Linux class room and to interact with the expert teachers.

Application for the course can be sent latest 19.02.2017. The course is aimed at PhD-students and postdocs working on structural biology projects using X-ray or neutron diffraction methods.  The application should include a motivation letter and a letter from the supervisor. Detailed information on how to apply, including a list of confirmed lectures and tutorials, is available at http://www.oulu.fi/biocenter/instruct-nac/courses/oulu. The detailed program is also provided at this www-page.  Most lectures are in the morning. Please contact the organers if you would like to attend the lectures, without registrating for the course.

Further information:

http://www.oulu.fi/biocenter/instruct-nac/courses/oulu